故事讲述患有强迫症的天才侦探蒙克的故事。他回来侦破最后一起案件，案件涉及他的继女莫莉，她是一名记者，正在为婚礼做准备。

　　It's 1998 and over the course of one 12 Hour Shift at an Arkansas Hospital, A Junkie Nurse (Angela Bettis), Her Scheming Cousin (Chloe Farnworth) and a group of black market Organ-Trading criminals (Mick Foley, David Arquette, Dusty Warren) start a heist that could lead to all of their demise.